The inhibitory effect of aqueous and alcoholic extract of Lavandula Officinalis L. on Some type of Pathogenic

Abstract

The purpose of this study is to know the inhibitory ability of alcoholic and aqueous extracts of lavender leaves Lavandula Officinalis L. to the growth of some human pathogenic organisms represented by two types of bacteria, Candida Albicans and Escherichia coli (E. coli) and Klebsiella pneumonia (Kleb). Ethanol and distilled water were used as solvents for extraction at concentrations of 0, 25, 50, and 100 mg ml^-1 for each. The alcoholic and aqueous extracts showed an inhibitory effect on the growth of the three species at a concentration of 100 mg ml-1, and the aqueous extract showed an inhibitory effect on Candida and Kleb at concentrations of 25 or 50 mg mL^-1. The concentrations showed variation in their inhibitory effect on pathogenic organisms, as the alcoholic extract at a concentration of 100 mg ml^-1 inhibited the growth of Candida and E. coli with a larger inhibitory diameter than the aqueous extract, and the aqueous extract at a concentration of 100 mg ml^-1 inhibited the growth of Kleb with a larger diameter than the alcoholic extract. GC-MAS analysis of the volatile oil sample of lavender leaves showed the appearance of some compounds with an important effect on the inhibitory activity, such as 1,8-cineole, alpha-pinene, beta-pinene, Camphor, and Terpineol.